Sex differences and sex-specific regulation of motivated behavior by Melanin-concentrating hormone: a short review

Table 2 A comparison of maternal and parental behaviors after MCH and MCHR1 manipulations in female and male rodents

Behavior	Species	Sex	Area	Manipulation	Effect	References
Pup retrieval	Mice	Female, unmated	Systemic	MCHR1 knockout	Decreased	[3]
Pup retrieval	Mice	Female, unmated	Systemic	MCH knockout	Decreased	[3]
Pup retrieval	Rats	Female, postpartum	mPOA	MCH microinjection	Decreased	[10]
Pup interaction	Mice	Female, unmated	Systemic	MCHR1 knockout	Decreased	[3]
Pup interaction	Mice	Female, unmated	Systemic	MCH knockout	Decreased	[3]
Pup mortality	Mice	Female, postpartum	Systemic	MCH knockout	Increased	[39]
Pup mortality	Mice	Female, postpartum	Systemic	MCH knockout	Increased	[1]
Pup aggression	Mice	Male, unmated	Systemic	MCH knockout	Increased	[39]
Intruder aggression	Mice	Male, unmated	Systemic	MCH knockout	Increased	[39]
Crouching	Mice	Female, unmated	Systemic	MCH ablation	Decreased	[39]
Crouching	Mice	Male, unmated	Systemic	MCH ablation	Decreased	[39]
Crouching	Mice	Female, unmated	LHA	MCH chemogenetic activation	Increased	[39]
Crouching	Mice	Male, unmated	LHA	MCH chemogenetic activation	Increased	[39]
Crouching	Mice	Female, unmated	LHA	MCH optogenetic activation	Increased	[39]
Crouching	Mice	Male, unmated	LHA	MCH optogenetic activation	Increased	[39]
Crouching	Mice	Female, unmated	Systemic	MCH knockout	Decreased	[39]
Hovering over, nursing posture, and time with pups	Rats	Female, postpartum	mPOA	MCH microinjection	No change	[10]
Nest building	Rats	Female, postpartum	mPOA	MCH microinjection	Decreased	[10]

ISSN: 2042-6410