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Table 1 A synopsis of MCH neuronal biochemical activation (reported as phosphorylated cyclic adenosine 3′,5′-monophosphate response element-binding protein (pCREB) expression levels) after a glucose challenge in different experimental groups; results from [63]

From: Sex differences and sex-specific regulation of motivated behavior by Melanin-concentrating hormone: a short review

Rat group

Experimental manipulation

Fed (saline)

Fasted (saline)

Fasted (glucose + 5 min)

Fasted (glucose + 15 min)

pCREB expression in lateral hypothalamic MCH neurons

 Intact male

Low

High

High

Low

 Orchiectomized male

Low

High

Low

 

 Orchiectomized male + testosterone

Low

High

High

 

 Orchiectomized male + estrogen

Low

High

Low

 

 Intact female proestrus + estrogen

Low

High

Low

Low

 Ovariectomized female

Low

High

High

 

 Ovariectomized female + testosterone

Low

High

Low

 

 Ovariectomized female + estrogen

Low

High

Low

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