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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis

Fig. 2

Scatter plot of beta estimates compared by interaction testing. Significant interactions are highlighted by colours and the respective candidate genes and SNPs are given in the legend on the right. Confidence intervals of SNPs without significant interaction overlap with the diagonal, stratum-specific interactions intersect with the lines x = 0 or y = 0 (grey horizontal and vertical lines), while stratum-related effects do not intersect with these lines. Panel A shows genetic sex interactions, with effect sizes in men and women at the x- and y-axis, respectively. Panel B shows genetic statin interaction, with effect sizes in statin-treated and -free individuals at the x- and y-axis, respectively

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