Fig. 5

Vocal repertoire of FXS pups. (A) Representative USVs calls classified into ten distinct categories based on a supervised-call classification neural network. (B, C) In the absence of FMRP, male mice exhibit a limited use of short calls in their vocal repertoire. (D, E) The vocal repertoire of female pups remains unaffected by the absence of FMRP. (B, D) Data are represented as a percentage utilization of each category of USVs for each group. (C, E) Data are shown as a bar graph (mean ± SEM) indicating the percentage utilization of each type of USV category for each group. Significance: * p-values < 0.05, full statistical details can be found in Suppl. Table 6. Sample sizes: (B-E) +/y males N = 9, -/y males N = 14, +/+ females N = 7, +/- females N = 13 and -/- females N = 6