Fig. 2

FMRP and sex influence body weight. On PND 10 and PND 13, the absence of FMRP resulted in decreased body weight for male mice (-/y) and increased weight for females (-/-) when compared to their respective control groups (+/y and +/+). Among the control groups, male mice (+/y) are typically heavier than female mice (+/+) at PND 10 but not PND 13. Single dots represent individual mice. The box plots present the data ranging from minimum to maximum values, with median and interquartile range (25–75 percentile) shown. The Mann-Whitney U test was applied for statistical analysis. p-values less than 0.05, indicating statistical significance, are marked on the graphs, while complete statistics can be found in Suppl. Table 1. Sample size 10 PND: +/y males N = 22, -/y males N = 21, +/+ females N = 12, +/- females N = 26 and -/- females N = 6. Sample size 13 PND: +/y males N = 10, -/y males N = 14, +/+ females N = 6, +/- females N = 12 and -/- females N = 7