Fig. 3
From: Different mechanisms underlie compulsive alcohol self-administration in male and female rats
Female rats show a higher resistance to shock-punished alcohol self-administration at progressively increasing shock intensities. A Mean reinforcers, B resistance score, C dose intake (± SEM) earned during 30-min punished self-administration sessions of 20% EtOH (FR2). D–F Resistance score distribution of punished alcohol self-administration across 10 days color coded for males (blue) and females (red) under increasing shock intensities (0.2, 0.25 and 0.3 mA). ##p < 0.01, ###p < 0.001, **p < 0.01