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Fig. 4 | Biology of Sex Differences

Fig. 4

From: The role of microRNAs in understanding sex-based differences in Alzheimer’s disease

Fig. 4

Differential miRNA expression profiles in meta-analyses of blood samples from female and male AD and control patients. A Volcano plot showing overexpressed miRNAs (orange dots, sixteen miRNAs) in female AD patients. MiRBase IDs corresponding to displayed numbers are listed in C. Horizontal dashed gray line indicates − log10FDR (0.05). B Volcano plot showing miRNAs underexpressed (blue dots, four miRNAs) and overexpressed (orange dots, eighteen miRNAs) in male AD patients. MiRBase IDs corresponding to displayed numbers are listed in C. Horizontal dashed gray line indicates − log10FDR (0.05). C Venn diagram showing the intersection of overexpressed miRNAs in female and male AD patients. D Plot comparing in both sexes the expression profiles of miRNAs exclusively altered in female AD patients. E Plot comparing in both sexes the expression profiles of miRNAs exclusively altered in male AD patients

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