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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Novel insight into the lipid network of plasma extracellular vesicles reveal sex-based differences in the lipidomic profile of alcohol use disorder patients

Fig. 2

Experimental design and lipidomic workflow. A Description of the experimental groups and the comparisons made. B In the lipidomic workflow, lipids were extracted for quantification and identification through LC–MS/MS after isolating EVs from human plasma. Following data normalization and lipid class annotation, exploratory and differential analyses assessed lipid abundance. A class enrichment analysis was also performed. The LINEX2 platform provided: (i) a reaction global network, (ii) the subgraph with the most significant average substrate-product change, and (iii) a target lipids list for further enrichment analysis using LION-web

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Biology of Sex Differences

ISSN: 2042-6410

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