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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Male versus female inflammatory response after brain death model followed by ex vivo lung perfusion

Fig. 6

Gene expression of endothelial nitric oxide synthase (eNOS) (A), C3 (B), interleukin-6 (C), and cytokine-induced neutrophil chemoattractant 1 (CINC-1) (D). Animals were submitted to brain death (BD—4 h), and their lungs were placed in the ex vivo lung perfusion (EVLP—4 h). As controls, Sham animals had their lungs placed in EVLP (4 h). The data are expressed as median and 95% percentile interval from five animals. P was calculated with calculated with two-way ANOVA. A P < 0.0001 by Sex, P = 0.0384 by BD and P = 0.016 Sex interaction with BD. B P = 0.2045 by Sex, P = 0.0608 by BD and P = 0.0743 Sex interaction with BD. C P = 0.0233 by Sex, P = 0.6344 by BD and P = 0.1874 Sex interaction with BD. D P = 0.0387 by Sex, P = 0.5193 by BD and P = 0.2595 Sex interaction with BD

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