Sex-based disparities in DNA methylation and gene expression in late-gestation mouse placentas

Table 4 Top X-chromosome DMRs

Gene symbol	Annotation	Change in methylation
Increased in male placentas
Firre	Intron	− 47.74
Firre	Intron	− 46.93
Firre	Intron	− 46.80
Xist	Non-coding	− 45.23
Firre	Intron	− 43.31
Firre	Intron	− 42.18
Xist	Non-coding	− 40.44
Firre	Intron	− 40.22
Firre	Intron	− 39.42
Xist	Non-coding	− 39.07
Xist	Non-coding	− 38.95
Ikbkg	Intron	− 38.63
Firre	Intron	− 38.53
Mir3620	Intron	− 38.31
Xist	Promoter-TSS	− 37.99
Firre	Intron	− 37.88
Firre	Intron	− 37.55
Firre	Intron	− 36.76
Firre	Intron	− 36.44
Firre	Intron	− 36.39
Increased in female placentas
Morf4l2	Intron	39.94
Pja1	Intron	39.38
Msl3	Intron	36.36
Efnb1	5′ UTR	36.02
Taf7l	Intron	35.63
Amer1	Intron	35.58
Ddx3x	Intron	35.23
Pja1	Intron	34.69
Atp6ap1	Intron	33.83
Las1l	Intron	32.74
Pgk1	Promoter-TSS	32.59
Sox3	3′ UTR	32.54
Mir1970	5′ UTR	31.52
Cnksr2	Intron	31.30
Sox3	Exon	31.29
Rab33a	Promoter-TSS	30.96
Msl3	Intron	30.44
Efnb1	Exon	30.43
Rai2	Intron	30.36
Gk	Promoter-TSS	30.31

ISSN: 2042-6410