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Table 2 Comparison of the mortality rates of \(\text{ER}\alpha\)+/+ and \(\text{ER}\alpha\)−/−mice during surgery, hypoxia, and post-HI

From: TrkB-mediated sustained neuroprotection is sex-specific and \(\text{ER}\alpha\)-dependent in adult mice following neonatal hypoxia ischemia

Mortality

\(\text{ER}\alpha\)+/+

(n)

\(\text{ER}\alpha\)−/−

(n)

Male

(68)

Female

(52)

Male

(32)

Female

(28)

During surgery

0

2

6

6

During hypoxia

0

0

3*

1

Post-HI

2

0

5*

4*

Total

2

2

14*

11*

  1. *p < 0.05 compared to \(\text{ER}\alpha\)+/+ using a generalized linear model with a logit link function
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Biology of Sex Differences

ISSN: 2042-6410

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