Fig. 2

SMR locus plot of the results of the SMR analysis between the CeD XWAS and the naïve female monocyte eQTLs. In the top panel, grey dots represent − log₁₀(P-values) for the female XWAS SNPs. Diamonds represent − log₁₀(P-values) for probes from the SMR analysis and filled diamonds show those that pass the HEIDI test. In the middle panel, the red crosses represent − log₁₀(P-values) for gene probes in the eQTL analysis. In the bottom panel, the location of the probes on the X chromosome is shown