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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Sex differences in mouse infralimbic cortex projections to the nucleus accumbens shell

Fig. 6

Entries made and sex differences in time spent in the reversal zone. A Females entered the reversal zone versus the previously active zone a greater number of times at 20 Hz and 30 Hz. The number of entries into the reversal zone was also greater at 30 Hz than 10 Hz. B Males entered the reversal zone significantly more only at 10 Hz and showed no differences in entries across stimulation frequencies. C Females spent more time in the reversal zone versus the acquisition zone at all three stimulus frequencies. They also spent more time in the reversal zone at 20 Hz and 30 Hz in comparison to 10 Hz. At 30 Hz, there was a sex difference in the time spent in the reversal zone. D In males, there were significant differences in the time spent in the reversal zone as compared with time spent in the acquisition at all stimulus frequencies. However, there were no differences across frequency. Representative track plots illustrate travel throughout the duration of the 30-Hz reversal trial for both E females and F males. The reversal zone is indicated by the solid blue square, and the previous acquisition zone is indicated by the dashed blue square

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