Fig. 4

Sex differences in optogenetic stimulation during acquisition. A In females, there were significant differences in the number of optogenetic stimulation trains received during each of the three frequencies. Sex differences in the number of stimulation trains occurred at both 20 Hz and 30 Hz. B There were no differences in the number of optogenetic stimulation trains received by males across frequencies. C Across all stimulus conditions, there were significant differences in the amount of time female received optogenetic stimulation. At both 20 Hz and 30 Hz, there were also sex differences in optogenetic stimulation time. D In males, increasing stimulation frequency had no effect on the amount of time optogenetic stimulation was received