Fig. 1

HFCD feeding induces more severe steatohepatitis in males than females, especially in CD1d^−/− mice. a Representative H&E staining of liver sections, scale bar: 100 µm; b serum levels of transaminases, ALT and AST; c intrahepatic triglycerides (TG) and cholesterol (Chol) levels; d liver-to-body ratio; and e NAS score were determined in CHOW, 6 weeks HFCD-fed Balb/c (WT) and CD1d-KO mice, males or females. n = 8–10. Data are expressed as mean ± SEM, *p < 0.05, **p < 0.005, ***p < 0.001 vs. corresponding HFCD-groups