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Fig. 8 | Biology of Sex Differences

Fig. 8

From: Sex differences in binge alcohol drinking and the behavioral consequences of protracted abstinence in C57BL/6J mice

Fig. 8

Sex, but not protracted abstinence from chronic binge drinking, impacts behavioral measures of coping strategy and negative affect tested 4–6 weeks following EtOH/H2O exposure. A–C Forced swim test (FST). Females displayed less % time immobile (A) and more time swimming (B) but not climbing (C) than males, regardless of alcohol history. D Tail suspension test (TST). Females displayed less % time passive than males. E Hot plate paw withdrawal. There was no effect of sex or alcohol history on the paw withdrawal latency for either low (52 °C) or high (58 °C) hot plate temperatures. **P < 0.01 in 2XANOVA main effects of and interactions between sex and EtOH and post hoc t-tests with H–S corrections between M and F

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