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Table 2 Plasma concentration of steroid hormones

From: Sex and age differences in social and cognitive function in offspring exposed to late gestational hypoxia

 

Normoxia

CIH

  

Puberty

Young Adult

 

Puberty

Young Adult

Corticosterone (ng/ml)

F

307.46 ± 107.24

322.22 ± 63.38

F

457.58 ± 203.25***

246.75 ± 63.89###

M **

168.94 ± 74.95 ##

168.32 ± 39.67##

M **

218.80 ± 92.28##

160.03 ± 57.16##

 

Normoxia

CIH

  

Puberty

Young Adult

 

Puberty

Young Adult

Estradiol (pg/ml)

F

26.70 ± 4.11

55.15 ± 48.92

F

40.85 ± 26.79

67.80 ± 42.65

 

M

42.74 ± 58.77

43.12 ± 30.50

M

39.99 ± 35.31

38.44 ± 18.53

 

Normoxia

CIH

  

Puberty

Young Adult**

 

Puberty

Young Adult**

Testosterone (ng/ml)

F

0.51 ± 0.30

0.99 ± 0.48

F

0.70 ± 0.31

1.52 ± 0.95 ###

M **

1.52 ± 0.67 ##

2.92 ± 1.08##, ###

M**

1.62 ± 0.62##

2.99 ± 0.69##, ###

  1. All values presented as mean ± SD without normalization. All values normalized by square root transformation for analysis. Analyzed by Two-way ANOVA with Fisher’s LSD multiple comparisons tests. Corticosterone: n = 8–10/group; Estradiol: n = 5–9/group; Testosterone: n = 7–10/group. ANOVA significance within treatment group (i.e., Normoxia or CIH) indicated by: * = CIH, ** = sex or age, *** = interaction of age/CIH; Post-hoc significance within treatment group (i.e., Normoxia or CIH) indicated by: # = versus normoxia, ## = versus female, ### = versus puberty; p ≤ 0.05