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Table 1 Expression of proteins associated with social and cognitive function within the dorsal hippocampus

From: Sex and age differences in social and cognitive function in offspring exposed to late gestational hypoxia

  

Normoxia

CIH

   

Puberty

Young adult**

 

Puberty

Young adult **

CA1

Dopamine Transporter (DAT)

F

91.27 ± 29.25

71.10 ± 18.23 ##

F

104.42 ± 45.78

68.21 ± 31.17 ##

M *

84.76 ± 26.75

90.48 ± 25.92 #

M*

92.81 ± 13.74

105.94 ± 20.84 #

  

Puberty

Young adult

 

Puberty

Young adult

Monoamine Oxidase A (MAO-A)

F

49.33 ± 13.76

52.03 ± 45.22

F

53.28 ± 14.38

43.49 ± 34.70

M

58.68 ± 38.36

54.45 ± 42.02

M

55.20 ± 25.98

43.79 ± 51.97

  

Puberty

Young adult**

 

Puberty

Young adult**

NMDA Receptor 2A (NR2A)

F

75.11 ± 14.95

54.20 ± 19.37##

F

76.22 ± 27.92

51.17 ± 22.55##

M

73.82 ± 13.56

70.74 ± 24.76

M

64.43 ± 18.25

60.33 ± 25.83

  

Normoxia

CIH

DG

  

Puberty

Young adult

 

Puberty

Young adult

Doublecortin (DC)

F

99.27 ± 43.29

70.64 ± 45.29

F

79.45 ± 20.34

75.99 ± 46.04

M

94.30 ± 40.15

77.03 ± 31.08

M

103.62 ± 31.93

85.80 ± 23.07

  

Puberty

Young adult**

 

Puberty

Young adult**

Early Growth Response 1 (EGR-1)

F

106.71 ± 34.31

57.76 ± 28.22##

F

94.73 ± 19.25

49.51 ± 28.00##

M

107.57 ± 26.71

59.96 ± 27.87##

M

117.85 ± 10.63

76.40 ± 37.54##

  1. All values represent percentage of Beta Actin expression. All values presented as mean ± SD. Analyzed by Two-way ANOVA with Fisher’s LSD multiple comparisons tests, n = 6/group. ANOVA significance within treatment group (i.e., Normoxia or CIH) indicated by: * = sex, ** = age; Post-hoc significance within treatment group (i.e., Normoxia or CIH) indicated by: # = versus female, ## = versus puberty; p ≤ 0.05