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Table 1 Demographic and clinical data of AS patients

From: Sex-specific role of galectin-3 in aortic stenosis

Variables

Total

Men

Women

p-value

n (%)

226

139 (61.50)

87 (38.50)

n/a

Age (median [IQR])

72 [66–78]

70 [65–77]

77 [69–80]

0.000

BS, cm2 (mean ± SD)

1.81 ± 0.20

1.90 ± 0.16

1.67 ± 0.16

0.000

HTA, n (%)

156 (69.0)

97 (69.8)

59 (67.8)

0.756

Renal insuficiency, n (%)

14 (6.2)

7 (5)

7 (8)

0.361

Creatinine (mg/dL)

0.86 [0.76–1.01]

0.91 [0.81–1.1]

0.79 [0.70–0.94]

0.000

NYHA class, n (%)

 I

24 (10.6)

19 (13.7)

5 (5.7)

0.076

 II

137 (60.6)

91 (65.5)

46 (52.9)

0.069

 III

61 (27.0)

28 (20.1)

33 (37.9)

0.005

 IV

4 (1.8)

1 (0.7)

3 (3.4)

0.160

Mean gradient (mmHg)

50.2 (13.6)

49.7 (13.6)

50.9 (13.7)

0.559

Max gradient (mmHg)

78.8 (19.6)

78.6 (19.7)

79.1 (19.7)

0.879

Drug medicines

 ACEi, n (%)

58 (25.7)

36 (25.9)

22 (25.3)

0.918

 ARB, n (%)

54 (23.9)

34 (24.5)

20 (23)

0.801

 Diuretics, n (%)

122 (54)

67 (48.2)

55 (63.2)

0.026

 β-blockers, n (%)

65 (28.8)

41 (23.5)

24 (27.6)

0.758

 Statins, n (%)

141 (62.4)

100 (71.9)

41 (47.1)

0.000

  1. n/a no applicable, IQR interquartile range, SD standard deviation, BS body surface, HTA arterial hypertension, NYHA New York Heart Association class, eGFR estimated glomerular filtration rate, ACEi Angiotensin-converting enzyme inhibitor, ARB Angiotensin II receptor blocker