Fig. 4
From: Endothelin mediates sex-differences in acclimation to high salt diet in rats
Dual ET receptor antagonism increased blood pressure in both male and female rats. Mean arterial blood pressure measured in NS or HS-fed male and female rats treated with and without the dual ET receptor antagonist (A-182086, 10 mg/kg/day). N = 7 per group. Two-way repeated-measures ANOVA with post hoc Sidak’s test. P values < 0.05 from post hoc test are displayed on graph. Endothelin receptor (ET), high salt (HS), and normal salt (NS)