Fig. 3
From: Endothelin mediates sex-differences in acclimation to high salt diet in rats
Dual ET receptor antagonist treatment increased serum ET-1 levels in both male and female rats to a comparable extent. Serum levels of ET-1 peptide measured in HS-fed male and female rats treated with or without the dual ET receptor antagonist (A-182086, 10 mg/kg/day). N = 6 per group. Two-way ANOVA with post hoc Sidak’s test. P values < 0.05 from post hoc test are displayed on graph. Endothelin receptor (ET) and Endothelin-1 (ET-1)