Fig. 2

Characteristics of the seizures induced by different intensities of ECS treatment in adolescent and adult female rats. Time spent in tonic (s) and clonic (s) phases, or in recovery (s) during ECS exposure in (a–c) adolescence and (d–f) adulthood across days 2 and 4 of treatment, or (g–i) when comparing the average of all days for each phase in adolescence vs. adulthood. Data represents mean ± SEM of the time (s) spent in each phase. Individual values are shown for each rat (symbols). Two-way RM ANOVAs did not detect any significant changes in adolescence or adulthood. Two-way ANOVAs (independent variables: ECS intensity, Age) followed by Sidak's multiple comparisons tests: *p < 0.05 and ***p < 0.001 vs. same intensity-dose adolescent rats. Significant effects of Age: ^##p < 0.01 and ^###p < 0.001 when comparing adulthood vs. adolescence