Fig. 6

Transcriptional characterization of genes associated to physical weakness, in the context of aging. A Venn diagram displaying the number of differentially expressed genes in the weakest vs. fittest female older adults, and the fraction of those differentially expressed genes that were also differentially expressed in old vs. young females. B Heatmap displaying the normalized counts of genes that were differentially expressed in the weakest vs. fittest female older adults. C Principal component analysis plot based on the 344 differentially expressed genes in the weakest vs. fittest female older adults. Circles around individual data points represent 95% confidence regions per group D Venn diagram displaying the number of differentially expressed genes in the weakest vs. fittest male older adults, and the fraction of those differentially expressed genes that were also differentially expressed in old vs. young males. E Heatmap displaying the normalized counts of genes that were differentially expressed in the weakest vs. fittest male older adults. F Principal component analysis plot based on the 299 differentially expressed genes in the weakest vs. fittest female older adults. Circles around individual data points represent 95% confidence regions per group