Fig. 3

Differences in proliferation, phenotypes, genomic alterations and telomere length between DKC1-high and low ccRCC tumors. The analysis was performed on the total of 530 patients (both sexes), female and male patients in the TCGA ccRCC cohort, respectively. A and B Proliferation as determined using Ki-67 expression and cell cycle ssGSEA score, respectively. C Cancer stemness. D EMT. E Aneuploidy score. F Intratumor heterogeneity score. G–I Alterations in ccRCC-specific and non-specific genes in the total, female and male patients. J Telomere length. Wilcox sum test was used for A–F and J, while Fisher’s exact test was for G–I