Characteristic | Men (n = 941) | Women (n = 1407) | ||||
---|---|---|---|---|---|---|
Obstructive CAD (−) (n = 517) | Obstructive CAD (+) (n = 424) | P value | Obstructive CAD (−) (n = 907) | Obstructive CAD (+) (n = 500) | P value | |
Age, years | 57.0 ± 11.6 | 62.6 ± 10.2 | < 0.001 | 62.4 ± 10.3 | 68.1 ± 9.1 | < 0.001 |
BMI, kg/m2 | 25.0 ± 3.1 | 25.2 ± 3.1 | 0.536 | 25.1 ± 3.7 | 25.0 ± 3.7 | 0.389 |
Waist circumference, cm | 86.0 ± 9.0 | 87.6 ± 10.1 | 0.082 | 82.0 ± 10.1 | 83.9 ± 9.6 | 0.016 |
Systolic blood pressure, mmHg | 126 ± 16 | 130 ± 18 | 0.005 | 124 ± 17 | 130 ± 20 | < 0.001 |
Diastolic blood pressure, mmHg | 79.7 ± 11.5 | 78.2 ± 11.7 | 0.088 | 75.1 ± 11.3 | 76.1 ± 12.2 | 0.188 |
Heart rate, per minute | 75.1 ± 13.9 | 74.3 ± 13.2 | 0.426 | 74.2 ± 12.2 | 74.9 ± 13.5 | 0.418 |
Cardiovascular risk factors, % | ||||||
Hypertension | 47.4 | 61.1 | < 0.001 | 49.3 | 67.7 | < 0.001 |
Diabetes mellitus | 19.6 | 36.2 | < 0.001 | 17.8 | 34.6 | < 0.001 |
Dyslipidemia | 26.0 | 24.5 | 0.653 | 27.3 | 25.6 | 0.526 |
Current smoking | 31.5 | 39.1 | 0.021 | 4.9 | 4.8 | 0.972 |
Obesity (BMI ≥ 25 kg/m2) | 51.1 | 52.0 | 0.807 | 46.0 | 46.4 | 0.889 |
Laboratory findings | ||||||
WBC, per microliter | 6764 ± 2118 | 7175 ± 2098 | 0.005 | 6471 ± 2237 | 7405 ± 3156 | < 0.001 |
Hemoglobin, g/dL | 14.5 ± 1.5 | 14.0 ± 1.6 | < 0.001 | 12.9 ± 1.3 | 12.5 ± 1.6 | < 0.001 |
GFR, mL/min/1.73 m2 | 82.1 ± 19.4 | 80.8 ± 23.4 | 0.356 | 84.1 ± 27.5 | 81.9 ± 31.6 | 0.204 |
Fasting glucose, mg/dL | 113 ± 36 | 127 ± 52 | < 0.001 | 112 ± 40 | 129 ± 53 | < 0.001 |
Glycated hemoglobin, % | 5.97 ± 1.05 | 6.58 ± 1.38 | < 0.001 | 6.04 ± 0.99 | 6.39 ± 1.26 | < 0.001 |
Total cholesterol, mg/dL | 165 ± 40 | 162 ± 43 | 0.218 | 171 ± 43 | 173 ± 46 | 0.491 |
LDL cholesterol, mg/dL | 102 ± 34 | 100 ± 38 | 0.435 | 101 ± 35 | 107 ± 37 | 0.018 |
HDL cholesterol, mg/dL | 45.2 ± 12.2 | 41.6 ± 10.6 | < 0.001 | 51.1 ± 13.9 | 45.8 ± 11.1 | < 0.001 |
Triglyceride, mg/dL | 155 ± 108 | 152 ± 116 | 0.776 | 123 ± 75 | 133 ± 105 | 0.079 |
C-reactive protein, mg/dL | 2.74 ± 11.5 | 1.39 ± 3.56 | 0.101 | 0.79 ± 2.47 | 1.28 ± 4.22 | 0.081 |
Concomitant medications, % | ||||||
Antiplatelet | 36.9 | 63.8 | < 0.001 | 43.1 | 65.9 | < 0.001 |
Calcium channel blocker | 29.1 | 39.6 | 0.002 | 33.5 | 34.9 | 0.632 |
Beta-blocker | 15.9 | 32.3 | < 0.001 | 23.5 | 39.8 | < 0.001 |
RAS blocker | 33.0 | 47.3 | < 0.001 | 34.5 | 49.0 | < 0.001 |
Statin | 42.6 | 62.7 | < 0.001 | 52.4 | 64.3 | < 0.001 |