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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Estrogen modulation of pain perception with a novel 17β-estradiol pretreatment regime in ovariectomized rats

Fig. 1

Establishment of different estrogen pretreatment regimes. a Fluctuations of serum estrogen levels in rats with different replacement paradigms. The day of OVX surgery was defined as day 0, and arrows indicate the day of estrogen pellets implantation. From day 33 on, the groups showed different estrogen alteration trends. Data are showed as mean ± SEM. b Illustration of the substitution paradigms: control (intact) group was omitted from the diagrams for the convenient of comprehension

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